Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-4' and Ligand = 'BDBM50088454'
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088454(NS3920, 4 | CHEMBL306387 | 1-(6-bromopyridin-3-yl)...)
Affinity DataEC50:  64.6nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088454(NS3920, 4 | CHEMBL306387 | 1-(6-bromopyridin-3-yl)...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
University of Copenhagen

LigandPNGBDBM50088454(NS3920, 4 | CHEMBL306387 | 1-(6-bromopyridin-3-yl)...)
Affinity DataKi:  0.320nMAssay Description:Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed