Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50143320'
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143320(2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]hept...)
Affinity DataEC50:  39.8nMAssay Description:Agonist activity at human recombinant alpha7 nAChR expressed in rat GH3 cells by calcium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50143320(2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]hept...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [125I-alpha]-Bungarotoxin from alpha-7 nAChR in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed