Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Neurotensin receptor type 2' and Ligand = 'BDBM85050'
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM85050(SR142948A | CAS_184162-64-9 | SR 142948A | SR14294...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [125I]neurotensin from rat NTS2 receptor expressed in CHO-K1 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM85050(SR142948A | CAS_184162-64-9 | SR 142948A | SR14294...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]NT at rat NTS2 overexpressed in CHOK1 cells after 30 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM85050(SR142948A | CAS_184162-64-9 | SR 142948A | SR14294...)
Affinity DataKi:  7nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 2 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM85050(SR142948A | CAS_184162-64-9 | SR 142948A | SR14294...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM85050(SR142948A | CAS_184162-64-9 | SR 142948A | SR14294...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at rat NTS2 stably expressed in CHOK1 cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM85050(SR142948A | CAS_184162-64-9 | SR 142948A | SR14294...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at rat NTS2 receptor expressed in CHO-K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed