Found 6 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, endothelial' and Ligand = 'BDBM50226527' TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 5.12E+4nMAssay Description:Inhibition of human eNOS assessed as reduction in L-[3H]-citrulline level using L-[3H]-arginine as substrate incubated for 1 hrMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.04E+5nMAssay Description:Inhibition of human eNOS using L-argininge as substrate preincubated for 15 mins followed by NADPH addition and measured after 20 mins by OPA/NAC rea...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
University Of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of bovine recombinant eNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analys...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
University Of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
Affinity DataIC50: 3.84E+5nMAssay Description:Inhibition of recombinant bovine eNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.10E+6nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
University Of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
Affinity DataIC50: 1.10E+6nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
