Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM497234'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals, LLC

US Patent
LigandPNGBDBM497234(US11001583, Compound 7)
Show SMILES CCOC[C@H](NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1)c1ccc(cc1)S(=O)(=O)CC
Show InChI InChI=1S/C31H42F3N3O4S/c1-5-41-19-27(22-9-13-26(14-10-22)42(39,40)6-2)36-30(38)23-15-24-18-37(29(20(3)4)28(24)35-16-23)17-21-7-11-25(12-8-21)31(32,33)34/h9-10,13-16,20-21,25,27,29H,5-8,11-12,17-19H2,1-4H3,(H,36,38)/t21-,25-,27-,29-/m0/s1
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid