Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM498074'
TargetNuclear receptor ROR-gamma(Human)
Eli Lilly

US Patent
LigandChemical structure of BindingDB Monomer ID 498074BDBM498074((5′S) N-[4-(Ethylsulfonyl)benzyl]-5′-m...)
Affinity DataKi:  5.88nMAssay Description:Receptor competition binding assays are run in a buffer made up of DPBS (1 L) (Hyclone #SH30028.03), 2.2 g BSA Fraction v (Roche #9048-46-8), 100 mL ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Eli Lilly

US Patent
LigandChemical structure of BindingDB Monomer ID 498074BDBM498074((5′S) N-[4-(Ethylsulfonyl)benzyl]-5′-m...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]-25-hydroxycholesterol from His-Flag-tagged human RORgammat LBD (309 to 508 residues) expressed in Escherichia coli measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed