Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50012133'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50012133(CHEMBL3263699)
Affinity DataIC50:  31nMAssay Description:Displacement of [3H2]25-hydroxycholesterol from RoRc-LBD (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50012133(CHEMBL3263699)
Affinity DataIC50:  71nMAssay Description:Displacement of [3H2]25-hydroxycholesterol from human RORc-LBD after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50012133(CHEMBL3263699)
Affinity DataEC50:  150nMAssay Description:Inverse agonist activity at an N-terminal 6xHis-GST-tag human RORc-LBD assessed as inhibition of recruitment of the SRC1 co-activator peptide after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed