Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM205105'
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM205105(3-methyl-2-{[(3r,6r)-6- methyl-1-{[2-methyl-6-(2h-...)
Affinity DataKi:  0.200nMAssay Description:Radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430) in which the inhibition constant (Ki) is determ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM205105(3-methyl-2-{[(3r,6r)-6- methyl-1-{[2-methyl-6-(2h-...)
Affinity DataIC50:  12nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent