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Found 2 Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-beta' and Ligand = 'BDBM50390761'
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390761(CHEMBL2070459)
Affinity DataIC50:  1.80E+3nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from GST-tagged LXRbeta ligand binding domai...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390761(CHEMBL2070459)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at LXRbeta ligand binding domain expressed in HEK293 cells coexpressing GAL4 assessed as decrease in [3H]N-(4-(1,1,1,3,3,3-hexafl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed