Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor alpha' and Ligand = 'BDBM50314814'
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50314814(2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)met...)
Affinity DataEC50:  8nMAssay Description:Agonist activity against human Gal4-fussed PPARalpha in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50314814(2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)met...)
Affinity DataEC50:  8.80nMAssay Description:Agonist activity at human PPARalpha LBD (167-468) expressed in HEK293 cells coexpressing GAL4-DBD by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50314814(2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)met...)
Affinity DataIC50: 347nMAssay Description:Binding affinity to human His-tagged PPARalpha LBD (E196-Y468) expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed