Found 5 Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor gamma' and Ligand = 'BDBM28800' TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Co.
Bristol-Myers Squibb Co.
Affinity DataIC50: >1.50E+4nM EC50: 4.10E+3nMpH: 8.0 T: 2°CAssay Description:For PPARgamma, the percentage inhibition was calculated relative to rosiglitazone, which was used as the active site-specific competitive binder. Flu...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Co.
Bristol-Myers Squibb Co.
Affinity DataIC50: >1.50E+4nMAssay Description:Binding affinity to human His-tagged PPARgamma LBD (Q203-Y477) expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Co.
Bristol-Myers Squibb Co.
Affinity DataEC50: 2.40E+3nMAssay Description:Agonist activity at full length human PPARgamma expressed in HepG2 cells cotransfected with pBL-tk-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Co.
Bristol-Myers Squibb Co.
Affinity DataEC50: 4.10E+3nMAssay Description:Agonist activity at human PPARgamma LBD (176-477) expressed in HEK293 cells coexpressing GAL4-DBD by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Co.
Bristol-Myers Squibb Co.
Affinity DataEC50: 4.02E+3nMAssay Description:Agonist activity against human Gal4-fussed PPARgamma in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
