BindingDB PrimarySearch

Found 1 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform/Phosphoinositide 3-kinase regulatory subunit 5' and Ligand = 'BDBM12915'

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform/Phosphoinositide 3-kinase regulatory subunit 5(Homo sapiens (Human))
Pfizer

BDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)

IC50: 1.72E+3nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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PDB

3D Structure (crystal)