Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM50449964'
LigandPNGBDBM50449964(CHEMBL4174988)
Affinity DataEC50: >3.00E+3nMAssay Description:Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as C5a-induced reduction in phosphorylation of AKT at Ser473 residues preincubated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50449964(CHEMBL4174988)
Affinity DataIC50: 203nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed