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Found 3 Enz. Inhib. hit(s) with Target = 'Pituitary adenylate cyclase-activating polypeptide type I receptor' and Ligand = 'BDBM50250018'
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50250018(CHEMBL524852 | PACAP27)
Affinity DataIC50:  4.60nMAssay Description:Displacement of Ac-[125I]-PACAP27 from recombinant human PAC1 expressed in CHO cells after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50250018(CHEMBL524852 | PACAP27)
Affinity DataIC50:  8.30nMAssay Description:Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50250018(CHEMBL524852 | PACAP27)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed