Found 115 Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 2' and Ligand = 'BDBM50031467' TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 8.89E+3nMAssay Description:Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity at 5 uM active compound by Lineweaver-Burk plot analy...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 1.22E+4nMAssay Description:Competitive inhibition of mushroom tyrosinase polyphenol oxidase activity using L-DOPA as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 1.49E+4nMAssay Description:Competitive inhibition of mushroom tyrosinase diphenolase activity assessed as L-DOPA conversion to dopachrome by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activityMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 2.23E+4nMAssay Description:Inhibition of mashroom tyrosinaseMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 3.00E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as inhibition constant for compound-free enzyme using as L-tyrosine substrate by spectrophotometric analys...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 5.83E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as oxidation of L-DOPAMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of mushroom tyrosinase after 10 mins by L-DOPA oxidation assayMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 9.15E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopachrome formation after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 9.18E+3nMAssay Description:Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 minsMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 9.28E+3nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate by ELISAMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of mushroom tyrosine kinase assessed as oxidation of 0.25 mM L-3,4-dihydroxyphenylalanineMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 9.96E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate after 10 minsMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antibacterial activity against D-alanyl-D-alanine ligase from Streptococcus faecalis (ATCC 8043)More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopaquinone production after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of mushroom tyrosinase preincubated for 10 mins before addition of 1.7 mM L-tyrosine measured after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of mushroom tyrosinase using TBC as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plotMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate preincubated for 10 mins with substrate followed by enzyme addition measured after 15...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase pre-incubated for 30 mins before L-DOPA substrate addition and measured after 1 min by spec...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.25E+4nMT: 2°CAssay Description:Mushroom tyrosinase using either L-DOPA or L-tyrosine as substrate. In spectrophotometric experiments, enzyme activity was monitored by dopachrome f...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate incubated for 10 mins by UV-Visible spectrophotometric anal...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate preincubated with substrate for 10 mins followed by protein...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate after 5 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as formation of L-DOPA chrome preincubated for 10 mins followed by addition of s...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured for 20 minsMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate after 5 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of mashroom tyrosinaseMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as decrease in L-DOPA chrome formation using L-DOPA as substrate preincubated with...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrateMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate preincubated with substrate for 10 mins followed by protein addition...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome production using L-DOPA as substrate after 5 mins by spectrophotometric analysi...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate assessed as formation of DOPAchrome preincubated for 10 mins followe...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in diphenolase activity using L-DOPA substrate pre-incubated for 20 mins at 30 degCMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrateMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 20 mins followed by substr...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 20 mi...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University of Technology Sydney
Curated by ChEMBL
University of Technology Sydney
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of mushroom tyrosinase preincubated for 20 minsMore data for this Ligand-Target Pair
