Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50273709'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50273709(2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidine-2-ylt...)
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-LO in PMNL cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50273709(2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidine-2-ylt...)
Affinity DataIC50: 730nMAssay Description:Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50273709(2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidine-2-ylt...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate incubated 5 to 10 mins prior to...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50273709(2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidine-2-ylt...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli by cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed