Report error Found 3 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50383655'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of 5-lipoxygenase in cell free S100 freshly isolated human PMNL cells assessed as inhibition of A23187-stimulated 5-LO product formation p...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of 5-lipoxygenase in human polynuclear leukocytes assessed as inhibition of A23187-stimulated 5-LO product formation preincubated for 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 127nMAssay Description:Inhibition of rat 5-LOX expressed in insect sf21 cells preincubated for 4 mins followed by Arachidonic acid addition and measured after 4 mins by FOX...More data for this Ligand-Target Pair
