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Found 5 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM89440'
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM89440(4-(4-chlorophenyl)butyl-diethyl-heptyl-ammonium;to...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM89440(4-(4-chlorophenyl)butyl-diethyl-heptyl-ammonium;to...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM89440(4-(4-chlorophenyl)butyl-diethyl-heptyl-ammonium;to...)
Affinity DataIC50:  12.6nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM89440(4-(4-chlorophenyl)butyl-diethyl-heptyl-ammonium;to...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM89440(4-(4-chlorophenyl)butyl-diethyl-heptyl-ammonium;to...)
Affinity DataIC50:  150nMAssay Description:Inhibitory concentration against IKr potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed