Report error Found 5 Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50458159'
Affinity DataIC50: 1.20nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1.30nMAssay Description:Inhibition of human gamma-secretase by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of gamma secretase isolated from human HeLa cell derived P2 membrane assessed as reduction in amyloid beta (1 to 40 residues) using recomb...More data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human gamma-secretaseMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as reduction in notch signaling by fetal thymus organ culture assayMore data for this Ligand-Target Pair
