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Found 5 Enz. Inhib. hit(s) with Target = 'Prostaglandin D2 receptor 2' and Ligand = 'BDBM50006830'
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006830(CHEMBL3236948)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of CRTH2 receptor-mediated chemotaxis in human basophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006830(CHEMBL3236948)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity to human CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006830(CHEMBL3236948)
Affinity DataIC50:  4nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006830(CHEMBL3236948)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at human recombinant CRTh2 expressed in CHO-K1 cells by cAMP TR FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006830(CHEMBL3236948)
Affinity DataIC50:  8nMT: 2°CAssay Description:Antagonist activity at CRTh2 in human peripheral blood assessed as inhibition of PGD2-induced eosinophil shape change at room temperature by flow cyt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed