Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase' and Ligand = 'BDBM50313218'
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313218(4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda*6...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human mPGES1 assessed as PGE2 level after 41 sec by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313218(4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda*6...)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of human mPGES1 in IL-1beta treated human FF cells assessed as blockade of PGH2 to PGE2 conversion after 50 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed