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Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP1 subtype' and Ligand = 'BDBM50160917'
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50160917(3-(3-(2-(benzyloxy)-5-chlorophenyl)thiophen-2-yl)b...)
Affinity DataKi:  0.300nMAssay Description:Antagonist activity against PGE2 activated EP1 receptor assessed as ability to inhibit intracellular calcium mobilisation by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50160917(3-(3-(2-(benzyloxy)-5-chlorophenyl)thiophen-2-yl)b...)
Affinity DataKi:  4nMAssay Description:Binding affinity against Prostaglandin E receptor was determined in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50160917(3-(3-(2-(benzyloxy)-5-chlorophenyl)thiophen-2-yl)b...)
Affinity DataKi:  70nMAssay Description:Binding affinity against Prostaglandin E receptor in presence of 2% human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50160917(3-(3-(2-(benzyloxy)-5-chlorophenyl)thiophen-2-yl)b...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed