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Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM50193921'
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi:  263nMAssay Description:Inhibition of EP3 receptor in presence of 0.005 % HASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi:  280nMAssay Description:Binding affinity to EP3 receptor in presence of HSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed