Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50101822'
TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

US Patent
LigandChemical structure of BindingDB Monomer ID 50101822BDBM50101822(CHEMBL64804 | PGE2, 15-epi | (Z)-7-[(1R,2R,3R)-3-H...)
Affinity DataEC50:  0.0500nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 ul of reduced serum medium containing 0.5% FBS. Place the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

US Patent
LigandChemical structure of BindingDB Monomer ID 50101822BDBM50101822(CHEMBL64804 | PGE2, 15-epi | (Z)-7-[(1R,2R,3R)-3-H...)
Affinity DataKi:  0.140nM IC50: 0.380nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

US Patent
LigandChemical structure of BindingDB Monomer ID 50101822BDBM50101822(CHEMBL64804 | PGE2, 15-epi | (Z)-7-[(1R,2R,3R)-3-H...)
Affinity DataEC50:  0.480nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101822BDBM50101822(CHEMBL64804 | PGE2, 15-epi | (Z)-7-[(1R,2R,3R)-3-H...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity towards mouse Prostanoid EP4 receptor in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed