Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50333748'
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333748(CHEMBL1644003 | N,N,5,7-tetramethyl-3-(4-(2-(3-tos...)
Affinity DataKi:  0.540nMAssay Description:Binding affinity to EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333748(CHEMBL1644003 | N,N,5,7-tetramethyl-3-(4-(2-(3-tos...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333748(CHEMBL1644003 | N,N,5,7-tetramethyl-3-(4-(2-(3-tos...)
Affinity DataKi:  2.60nMAssay Description:Ratio of Ki for EP4 receptor to EP4 receptor in presence of 10% HSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333748(CHEMBL1644003 | N,N,5,7-tetramethyl-3-(4-(2-(3-tos...)
Affinity DataIC50:  1.20nMAssay Description:Antagonist activity at human EP4 receptor in HEK293 cells by cell-based functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed