Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with Target = 'Prostaglandin F2-alpha receptor' and Ligand = 'BDBM50035622'
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataKi:  119nMAssay Description:Inhibitory Binding constant (n=2) to Prostanoid FP receptor expressed in bovine corpus luteumMore data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(BOVINE)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataKi:  129nMAssay Description:Binding affinity for Prostanoid FP receptor of bovine corpus luteumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(BOVINE)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]PGF2 alpha from FP receptor in bovine corpus luteum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [3H]-PGF2-alpha from human FP-receptor expressed in CHO-KI cellsMore data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataIC50:  3nMAssay Description:In vitro binding of the compound at FP human prostaglandin receptor using [3H]-PGF-2 alpha as radioligandMore data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataIC50:  7nMAssay Description:Affinity for human Prostanoid FP receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataIC50:  43nMAssay Description:Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in ovine luteal cells (OLC)More data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(BOVINE)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataIC50:  140nMAssay Description:Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataEC50:  79nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=100%)More data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataEC50:  24.5nMAssay Description:Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cellsMore data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(MOUSE)
Theravance

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at FP receptor in mouse 3T3 fibroblast cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(MOUSE)
Theravance

Curated by ChEMBL
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataEC50:  24.5nMAssay Description:Agonist activity at FP receptor in Swiss mouse 3T3 cells assessed as [3H]-IP accumulation by scintillation countingMore data for this Ligand-Target Pair