Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50110164'
TargetProstaglandin G/H synthase 2(Human)
Zafes/Liff/Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50110164({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant COX2 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zafes/Liff/Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50110164({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zafes/Liff/Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50110164({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by microplate reader...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zafes/Liff/Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50110164({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...)
Affinity DataKi:  1.21E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zafes/Liff/Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50110164({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed