Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50148911'
TargetProstaglandin G/H synthase 2(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148911BDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148911BDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148911BDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of COX2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148911BDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of COX2-catalyzed prostaglandin biosynthesis after 10 mins of preincubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed