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Found 3 Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 1' and Ligand = 'BDBM50109063'
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109063((3-Azepan-1-yl-propyl)-benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50:  140nMAssay Description:Antagonistic activity against thrombin receptor, inhibition of secreted radiolabeled [3H]-5-HT from washed human platelets stimulated by 3 microM thr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109063((3-Azepan-1-yl-propyl)-benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50:  290nMAssay Description:Inhibition of secretion of radiolabeled serotonin from washed human platelets stimulated by 1 nM thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109063((3-Azepan-1-yl-propyl)-benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of secretion of radiolabeled serotonin from washed human platelets stimulated by 1 nM thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed