Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 1' and Ligand = 'BDBM50380012'
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50380012(CHEMBL2012497)
Show SMILES CC[C@@H]1[C@@H](C)C[C@@H]2[C@@H]([C@@H](C)OC2=O)[C@H]1\C=C\c1ccc(cn1)-c1cccc(Cl)c1Cl
Show InChI InChI=1S/C25H27Cl2NO2/c1-4-18-14(2)12-21-23(15(3)30-25(21)29)20(18)11-10-17-9-8-16(13-28-17)19-6-5-7-22(26)24(19)27/h5-11,13-15,18,20-21,23H,4,12H2,1-3H3/b11-10+/t14-,15+,18+,20-,21+,23-/m0/s1
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]haTRAP from human PAR1 after 1 hr by TopCount scintillation countingMore data for this Ligand-Target Pair