Found 3 Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 4' and Ligand = 'BDBM176005' TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataEC50: 2.5nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataEC50: 2.5nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
