Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM32659'
TargetProthrombin(Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32659(m-chlorobenzylamide, 8)
Show SMILES CC(=O)N[C@H](CC1CCCCC1)C(=O)N1CCCC1C(=O)NCc1cccc(Cl)c1
Show InChI InChI=1S/C23H32ClN3O3/c1-16(28)26-20(14-17-7-3-2-4-8-17)23(30)27-12-6-11-21(27)22(29)25-15-18-9-5-10-19(24)13-18/h5,9-10,13,17,20-21H,2-4,6-8,11-12,14-15H2,1H3,(H,25,29)(H,26,28)/t20-,21?/m1/s1
Affinity DataKi:  8.70E+3nM ΔG°:  -28.9kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic inhibition of human thrombin was determined photometrically at 405 nm using the chromogenic substrate Pefachrom tPa. Reactions were performed...More data for this Ligand-Target Pair