Found 12 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM50142887'
Affinity DataKi: 500nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Src (unknown origin) using Src-family kinase bisamide rhodamine 110 peptide substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
University Of Dundee
Curated by ChEMBL
University Of Dundee
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of Src in the presence of 50uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 36.6nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 36.6nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of His6-tagged c-Src kinase domain using AEEEIYGEFEAKKKK as substrate pre-incubated for 10 mins before substrate addition measured after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of GST-tagged c-Src preincubated for 30 mins measured after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of c-Src after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of GST-fussed c-SRC after 30 minsMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
University Of Dundee
Curated by ChEMBL
University Of Dundee
Curated by ChEMBL
Affinity DataKd: 296nMAssay Description:Binding affinity to chicken 6-His tagged c-Src expressed in Escherichia coli Bl21 (DE3) assessed as dissociation constantMore data for this Ligand-Target Pair