Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM50397798'
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc

Curated by ChEMBL
LigandPNGBDBM50397798(CHEMBL2177836)
Affinity DataIC50:  5nMAssay Description:Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assayMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc

Curated by ChEMBL
LigandPNGBDBM50397798(CHEMBL2177836)
Affinity DataIC50:  27nMAssay Description:Inhibition of Akt1 in human A2780 cells assessed as phosphorylation of Akt at S473 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc

Curated by ChEMBL
LigandPNGBDBM50397798(CHEMBL2177836)
Affinity DataIC50:  32nMAssay Description:Inhibition of Akt 1 in human A2780 cells assessed as phosphorylation of Akt at T308 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc

Curated by ChEMBL
LigandPNGBDBM50397798(CHEMBL2177836)
Affinity DataIC50:  44nMAssay Description:Inhibition of Akt1 in human AN3CA cells assessed as phosphorylation of Akt at S473 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc

Curated by ChEMBL
LigandPNGBDBM50397798(CHEMBL2177836)
Affinity DataIC50:  45nMAssay Description:Inhibition of Akt 1 in human AN3CA cells assessed as phosphorylation of Akt at T308 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc

Curated by ChEMBL
LigandPNGBDBM50397798(CHEMBL2177836)
Affinity DataIC50:  220nMAssay Description:Inhibition of Akt1 in human AN3CA cells assessed as phosphorylation PRAS40 at T246 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc

Curated by ChEMBL
LigandPNGBDBM50397798(CHEMBL2177836)
Affinity DataIC50:  250nMAssay Description:Inhibition of Akt1 in human A2780 cells assessed as phosphorylation PRAS40 at T246 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair