Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM25198'
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)
Affinity DataIC50:  3nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)
Affinity DataIC50:  3.20nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of RIP2K in MDP-stimulated HEK-293 cells over-expressing NOD2 assessed as IL8 secretionMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of RIP2K in Pam2CSK4-stimulated HEK-293 cells over-expressing TLR2 assessed as IL8 secretionMore data for this Ligand-Target Pair