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Found
1
Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1a' and Ligand = 'BDBM510064'
Target
Replicase polyprotein 1a
(2019-nCoV)
Pfizer
US Patent
Ligand
BDBM510064
(N-[(2S)-1-({(1S)-1- Cyano-2-[(3S)-2-oxopyrrolidin-...)
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Affinity Data
Ki: 18nM
Assay Description:
The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...
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Target Info
PDB
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UniProtKB/SwissProt
B.MOAD
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Ligand Info
PC cid
PC sid
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Details
US Patent
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