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Found 4 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM11262'
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11262(dipeptidomimetic unsaturated ester 18d | ethyl (2E...)
Affinity DataKi:  9.04E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11262(dipeptidomimetic unsaturated ester 18d | ethyl (2E...)
Affinity DataKi:  9.05E+3nM ΔG°:  -28.8kJ/mole IC50:  1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11262(dipeptidomimetic unsaturated ester 18d | ethyl (2E...)
Affinity DataIC50:  1.00E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11262(dipeptidomimetic unsaturated ester 18d | ethyl (2E...)
Affinity DataEC50:  110nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed