Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM533526'
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533526(jm2c00120, Compound 25)
Affinity DataIC50: 19nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2022
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533526(jm2c00120, Compound 25)
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal 6His-tagged SARS-CoV 2 nsp14 N7-methyltransferase activity expressed in Escherichia coli C2566 using GpppAC4 synthetic RNA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed