Found 2 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab [1541-1855]' and Ligand = 'BDBM154573' TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
University Of Illinois At Chicago
University Of Illinois At Chicago
Affinity DataKi: 1.15E+4nM IC50: 1.09E+4nMpH: 7.5Assay Description:done in a single pass in black 384-well plates (Matrix Technologies). The SARS-PLpro enzyme (20 nM final concentration) was prepared in an assay buff...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
University Of Illinois At Chicago
University Of Illinois At Chicago
Affinity DataKd: 2.63E+4nMpH: 7.4Assay Description:Each PLpro enzyme was immobilized on a CM5 sensor chip using standard aminecoupling with running buffer HBS-P (10 mM HEPES, 150 mM NaCl, 0.05% surfac...More data for this Ligand-Target Pair
