Found 4 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50430022' TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma, Inc.
Curated by ChEMBL
Array BioPharma, Inc.
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma, Inc.
Curated by ChEMBL
Array BioPharma, Inc.
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of recombinant human GST-tagged BRAF V600E mutant expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma, Inc.
Curated by ChEMBL
Array BioPharma, Inc.
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylationMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array BioPharma, Inc.
Curated by ChEMBL
Array BioPharma, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of human recombinant N-terminus His-tagged BRAF expressed in Sf9 cells coexpressing CDC37 using biotinylated MEK as substrate and MgCl2 in...More data for this Ligand-Target Pair
