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Found 4 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM110726'
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM110726(US8614206, 252 | US8614206, 254 | US8614206, 352 |...)
Affinity DataKi:  0.00200nMpH: 7.2Assay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM110726(US8614206, 252 | US8614206, 254 | US8614206, 352 |...)
Affinity DataKi:  0.00800nMpH: 7.2Assay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM110726(US8614206, 252 | US8614206, 254 | US8614206, 352 |...)
Affinity DataKi:  0.00900nMpH: 7.2Assay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM110726(US8614206, 252 | US8614206, 254 | US8614206, 352 |...)
Affinity DataKi:  0.0511nMpH: 7.2Assay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
In DepthDetails US Patent