Found 14 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM2579'
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human PIM1 using KKRNRTLTK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human PIM1 using KKRNRTLTK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 10nMpH: 7.6 T: 2°CAssay Description:A coupled-enzyme assay was used to quantify the ADP generated in the kinase reaction with S6 peptide (RRRLSSLRA) as the phosphoacceptorsubstrate.More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human GST-tagged PIM1 by ELISAMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of Pim1 kinase (unknown origin) using substrate S3 after 50 mins by HTRF assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human Pim1 expressed in bacterial expression system using histone H1 as substrate after 30 mins by ADP-Glo reagent based lu...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of PIM1 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataKd: 3.20nMAssay Description:Binding constant for PIM1 kinase domainMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataKd: 15nMAssay Description:Average Binding Constant for PIM1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataKd: 1.40nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataKd: 3.20nMAssay Description:Binding constant for PIM1 kinase domainMore data for this Ligand-Target Pair