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Found 2 Enz. Inhib. hit(s) with Target = 'Smoothened homolog' and Ligand = 'BDBM50394402'
TargetSmoothened homolog(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50394402(CHEMBL2160072)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at Smo in mouse TM3 cells expressing Hh12 assessed as inhibition of 1 nM Ag1.5-induced Gli expression incubated for 30 mins prior...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50394402(CHEMBL2160072)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at Smo in mouse TM3 cells expressing Hh12 assessed as inhibition of 25 nM Ag1.5-induced Gli expression incubated for 30 mins prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed