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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM25872'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

Curated by ChEMBL
LigandPNGBDBM25872(2-{3-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]pro...)
Affinity DataIC50:  80nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Medicines Institute

LigandPNGBDBM25872(2-{3-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]pro...)
Affinity DataIC50:  80nMpH: 7.7 T: 2°CAssay Description:Ligand binding experiments were conducted in assay tubes containing radioligand, membrane tissue, and test compounds. Incubations were terminated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed