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Found 3 Enz. Inhib. hit(s) with Target = 'Thymidylate synthase' and Ligand = 'BDBM50186267'
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50186267(2'-deoxy-5'-uridylic acid | CHEMBL211312 | dUMP)
Affinity DataKi:  2.26E+3nMAssay Description:Inhibition of amethopterin-resistant Lactobacillus casei thymidylate synthetase-catalyzed 5-BrdUMP dehalogenation by absorbance analysis in absence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50186267(2'-deoxy-5'-uridylic acid | CHEMBL211312 | dUMP)
Affinity DataKi:  6.50E+3nMAssay Description:Competitive inhibition of purified mouse Ehrlich ascites tumor cell thymidylate synthetase using 5-[3H]-2'-deoxyuridine 5'-phosphate as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50186267(2'-deoxy-5'-uridylic acid | CHEMBL211312 | dUMP)
Affinity DataKi:  8.00E+3nMAssay Description:Competitive inhibition of purified calf thymus thymidylate synthetase using 5-[3H]-2'-deoxyuridine 5'-phosphate as substrate after 7 mins by double r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed