Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 7' and Ligand = 'BDBM507023'
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM507023(US11046671, VTX-133)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)-c1cccnc1
Show InChI InChI=1S/C22H26N4O/c1-3-10-26(11-4-2)22(27)19-12-17-8-7-16(18-6-5-9-24-15-18)13-20(17)25-21(23)14-19/h5-9,12-13,15H,3-4,10-11,14H2,1-2H3,(H2,23,25)
Affinity DataEC50:  1.86E+3nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid