Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM507045'
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C1=NCc2ccc(Cl)cc2N1
Show InChI InChI=1S/C25H28ClN5O/c1-3-9-31(10-4-2)25(32)19-11-16-5-6-17(12-21(16)29-23(27)13-19)24-28-15-18-7-8-20(26)14-22(18)30-24/h5-8,11-12,14H,3-4,9-10,13,15H2,1-2H3,(H2,27,29)(H,28,30)
Affinity DataEC50:  9nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid