Found 4 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM20504' TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Henan University
Curated by ChEMBL
Henan University
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced Ca2+ influx incubated for 30 mins by FLIPR meth...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of rat TRPV1More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Henan University
Curated by ChEMBL
Henan University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in HEK293 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Henan University
Curated by ChEMBL
Henan University
Curated by ChEMBL
Affinity DataEC50: 32nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
