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Found 3 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50061117'
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Scientus Pharma

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataIC50:  8.20E+4nMAssay Description:Agonist activity at ionomycin-stimulated TRPV1 (unknown origin) channel desensitization in presence of capsaicinMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Scientus Pharma

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataEC50:  6.20E+3nMAssay Description:Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluorescence as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Scientus Pharma

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataEC50:  6.20E+3nMAssay Description:Agonist activity at ionomycin-stimulated TRPV1 (unknown origin) activationMore data for this Ligand-Target Pair
In DepthDetails PubMed