Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Translocator protein' and Ligand = 'BDBM50363527'
TargetTranslocator protein(Rattus norvegicus (rat))
GE Healthcare

Curated by ChEMBL
LigandPNGBDBM50363527(CHEMBL1945412 | US9481685, [18F]FE-PBR)
Show SMILES CCN(CC)C(=O)C1Sc2ccccc2-c2c1c1ccccc1n2CCF
Show InChI InChI=1S/C22H23FN2OS/c1-3-24(4-2)22(26)21-19-15-9-5-7-11-17(15)25(14-13-23)20(19)16-10-6-8-12-18(16)27-21/h5-12,21H,3-4,13-14H2,1-2H3
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
GE Healthcare

Curated by ChEMBL
LigandPNGBDBM50363527(CHEMBL1945412 | US9481685, [18F]FE-PBR)
Show SMILES CCN(CC)C(=O)C1Sc2ccccc2-c2c1c1ccccc1n2CCF
Show InChI InChI=1S/C22H23FN2OS/c1-3-24(4-2)22(26)21-19-15-9-5-7-11-17(15)25(14-13-23)20(19)16-10-6-8-12-18(16)27-21/h5-12,21H,3-4,13-14H2,1-2H3
Affinity DataKi:  0.670nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Wistar rat heart homogenate after 15 minsMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
GE Healthcare

Curated by ChEMBL
LigandPNGBDBM50363527(CHEMBL1945412 | US9481685, [18F]FE-PBR)
Show SMILES CCN(CC)C(=O)C1Sc2ccccc2-c2c1c1ccccc1n2CCF
Show InChI InChI=1S/C22H23FN2OS/c1-3-24(4-2)22(26)21-19-15-9-5-7-11-17(15)25(14-13-23)20(19)16-10-6-8-12-18(16)27-21/h5-12,21H,3-4,13-14H2,1-2H3
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
GE Healthcare

Curated by ChEMBL
LigandPNGBDBM50363527(CHEMBL1945412 | US9481685, [18F]FE-PBR)
Show SMILES CCN(CC)C(=O)C1Sc2ccccc2-c2c1c1ccccc1n2CCF
Show InChI InChI=1S/C22H23FN2OS/c1-3-24(4-2)22(26)21-19-15-9-5-7-11-17(15)25(14-13-23)20(19)16-10-6-8-12-18(16)27-21/h5-12,21H,3-4,13-14H2,1-2H3
Affinity DataKi:  0.680nMpH: 7.4Assay Description:The compounds were screened for their affinity for PBR using a method adapted from Le Fur et al (Life Sci. 1983; USA 33: 449-57).The compounds to be ...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
GE Healthcare

Curated by ChEMBL
LigandPNGBDBM50363527(CHEMBL1945412 | US9481685, [18F]FE-PBR)
Show SMILES CCN(CC)C(=O)C1Sc2ccccc2-c2c1c1ccccc1n2CCF
Show InChI InChI=1S/C22H23FN2OS/c1-3-24(4-2)22(26)21-19-15-9-5-7-11-17(15)25(14-13-23)20(19)16-10-6-8-12-18(16)27-21/h5-12,21H,3-4,13-14H2,1-2H3
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]PK11195 from PBR receptor in Wistar rat heart homogenatesMore data for this Ligand-Target Pair